ORAL STREPTOCOCCI UTILIZE A SIGLEC-LIKE DOMAIN OF SERINE-RICH REPEAT ADHESINS TO PREFERENTIALLY TARGET PLATELET SIALOGLYCANS IN HUMAN BLOOD.

Oral streptococci utilize a Siglec-like domain of serine-rich repeat adhesins to preferentially target platelet sialoglycans in human blood.

Damaged cardiac valves attract blood-borne bacteria, and infective endocarditis is often caused by viridans group streptococci.While such bacteria use multiple adhesins to maintain their normal oral commensal state, recognition of platelet sialoglycans provides an intermediary for binding to damaged valvular endocardium.We use a customized sialogly

read more


Gata3 immunohistochemical staining is a useful marker for metastatic breast carcinoma in fine needle aspiration specimens

Aims: The utility of GATA3 immunohistochemistry (IHC) as Ginger an aid to the cytological diagnosis of metastatic breast carcinoma in fine needle aspiration (FNA) specimens was investigated.Materials and Methods: Cell block sections from 111 FNA cases of metastatic malignancy were stained for GATA3, including metastases from 43 breast and 44 nonmam

read more